Paper
Guideline-Grounded Evidence Accumulation for High-Stakes Agent Verification
Authors
Yichi Zhang, Nabeel Seedat, Yinpeng Dong, Peng Cui, Jun Zhu, Mihaela van de Schaar
Abstract
As LLM-powered agents have been used for high-stakes decision-making, such as clinical diagnosis, it becomes critical to develop reliable verification of their decisions to facilitate trustworthy deployment. Yet, existing verifiers usually underperform owing to a lack of domain knowledge and limited calibration. To address this, we establish GLEAN, an agent verification framework with Guideline-grounded Evidence Accumulation that compiles expert-curated protocols into trajectory-informed, well-calibrated correctness signals. GLEAN evaluates the step-wise alignment with domain guidelines and aggregates multi-guideline ratings into surrogate features, which are accumulated along the trajectory and calibrated into correctness probabilities using Bayesian logistic regression. Moreover, the estimated uncertainty triggers active verification, which selectively collects additional evidence for uncertain cases via expanding guideline coverage and performing differential checks. We empirically validate GLEAN with agentic clinical diagnosis across three diseases from the MIMIC-IV dataset, surpassing the best baseline by 12% in AUROC and 50% in Brier score reduction, which confirms the effectiveness in both discrimination and calibration. In addition, the expert study with clinicians recognizes GLEAN's utility in practice.
Metadata
Related papers
Gen-Searcher: Reinforcing Agentic Search for Image Generation
Kaituo Feng, Manyuan Zhang, Shuang Chen, Yunlong Lin, Kaixuan Fan, Yilei Jian... • 2026-03-30
On-the-fly Repulsion in the Contextual Space for Rich Diversity in Diffusion Transformers
Omer Dahary, Benaya Koren, Daniel Garibi, Daniel Cohen-Or • 2026-03-30
Graphilosophy: Graph-Based Digital Humanities Computing with The Four Books
Minh-Thu Do, Quynh-Chau Le-Tran, Duc-Duy Nguyen-Mai, Thien-Trang Nguyen, Khan... • 2026-03-30
ParaSpeechCLAP: A Dual-Encoder Speech-Text Model for Rich Stylistic Language-Audio Pretraining
Anuj Diwan, Eunsol Choi, David Harwath • 2026-03-30
RAD-AI: Rethinking Architecture Documentation for AI-Augmented Ecosystems
Oliver Aleksander Larsen, Mahyar T. Moghaddam • 2026-03-30
Raw Data (Debug)
{
"raw_xml": "<entry>\n <id>http://arxiv.org/abs/2603.02798v1</id>\n <title>Guideline-Grounded Evidence Accumulation for High-Stakes Agent Verification</title>\n <updated>2026-03-03T09:36:43Z</updated>\n <link href='https://arxiv.org/abs/2603.02798v1' rel='alternate' type='text/html'/>\n <link href='https://arxiv.org/pdf/2603.02798v1' rel='related' title='pdf' type='application/pdf'/>\n <summary>As LLM-powered agents have been used for high-stakes decision-making, such as clinical diagnosis, it becomes critical to develop reliable verification of their decisions to facilitate trustworthy deployment. Yet, existing verifiers usually underperform owing to a lack of domain knowledge and limited calibration. To address this, we establish GLEAN, an agent verification framework with Guideline-grounded Evidence Accumulation that compiles expert-curated protocols into trajectory-informed, well-calibrated correctness signals. GLEAN evaluates the step-wise alignment with domain guidelines and aggregates multi-guideline ratings into surrogate features, which are accumulated along the trajectory and calibrated into correctness probabilities using Bayesian logistic regression. Moreover, the estimated uncertainty triggers active verification, which selectively collects additional evidence for uncertain cases via expanding guideline coverage and performing differential checks. We empirically validate GLEAN with agentic clinical diagnosis across three diseases from the MIMIC-IV dataset, surpassing the best baseline by 12% in AUROC and 50% in Brier score reduction, which confirms the effectiveness in both discrimination and calibration. In addition, the expert study with clinicians recognizes GLEAN's utility in practice.</summary>\n <category scheme='http://arxiv.org/schemas/atom' term='cs.AI'/>\n <category scheme='http://arxiv.org/schemas/atom' term='cs.CL'/>\n <published>2026-03-03T09:36:43Z</published>\n <arxiv:primary_category term='cs.AI'/>\n <author>\n <name>Yichi Zhang</name>\n </author>\n <author>\n <name>Nabeel Seedat</name>\n </author>\n <author>\n <name>Yinpeng Dong</name>\n </author>\n <author>\n <name>Peng Cui</name>\n </author>\n <author>\n <name>Jun Zhu</name>\n </author>\n <author>\n <name>Mihaela van de Schaar</name>\n </author>\n </entry>"
}